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Apr 29, 2021 These 2 hormones&39; main role is to prepare the breasts for lactation bigger breast size, more alveoli, lactocytes, milk ducts, etc. Prolactin levels also increase steadily during the course of pregnancy but, contrary to progesterone and estrogen, they&39;re produced by the brain&39;s pituitary gland.. The galactogogue domperidone was started at 10 mg 3 times daily and titrated up to effect. She was encouraged to use an electric pump and to increase her frequency of pumping..